Baseline Noise

1

Poor nebulization

Increase the temperature of the nebulizer by 10 °C until the baseline noise decreases.

2

Insufficient evaporation

Increase the temperature of the evaporator by 10 °C until the baseline noise decreases.

Increase the evaporation gas flow rate.

Decrease the nebulization temperature.

3

Nonvolatile additive in mobile phase

Use a volatile mobile phase.

4

Pressure difference created inside nebulizer chamber

Ensure that the end of the liquid waste tube is not immersed in liquid.

Ensure that the exhaust tube at rear of unit is not blocked, or extraction is too strong.

5

Pump pulsations, especially in MicroBore applications where low flow rates are used

Use a pulse free pump.

Increase the backpressure on the pump by fitting a backpressure column between the pump and the injection valve.

Use a pulse dampener directly after the pump in the system.