The Agilent InfinityLab LC Series Vialsampler is designed for use with other modules of the Agilent InfinityLab LC Series, 1200 Series, and 1100 Series LC, as well as with other LC systems with adequate remote-control capabilities. The Vialsampler can be controlled from any computer with a suitable chromatography data system (for example, Agilent OpenLab CDS, MassHunter) or via an Agilent local control module (InfinityLab Companion or Agilent 1200 Infinity Instant Pilot).
The 1290 Infinity III Vialsampler (G7129B) can be operated at up to 1300 bar. The two 1260 Infinity III Vialsampler variants (G7129A and G7129C) are limited to a maximum system pressure of 600 and 800 bar, respectively.
The Vialsampler can accommodate two vial drawers, providing space for up to 132 samples. The two cartesian vial drawers allow for the use of either 66 × 2 mL or 18 × 6 mL vials. A pair of classic vial drawers with a numerical vial assignment system is also available, each capable of hosting 50 × 2 mL vials. The classic vial drawers are designed to ease method transfer from older Agilent samplers. The Vialsampler can also be equipped with an external tray, which can be beneficial for automation. The Agilent walk-up solution fully supports the external tray.
The Vialsampler features a robotic gripper arm for the transport of vials, driven by four stepper motors to ensure the highest precision and flexibility for the transport movement.
The default configuration of the analytical head and sample loop allows an injection range from 0.1 – 20 μL for the 1290 Infinity III Vialsampler and 0.1 – 100 μL for the 1260 Infinity III Vialsamplers. An analytical head with extended volume is also available for injection volumes from 0.1 – 900 μL, and can be operated at up to 400 bar. With the Multidraw Kit, the maximum injection volume can even reach 1800 μL.
The 2-position/6-port injection valve is driven by a high-speed, hybrid stepper motor, ensuring smooth switching between the main pass and bypass positions. Thanks to the flow-through design of the Vialsampler, the eluent continuously rinses the component parts of the sample introduction system. This, together with the automated needle wash function for rinsing the outer surface of the needle, ensures the lowest level of carry over for each analysis. For advanced delay volume reduction, the injection valve can be programmed to automatically switch back to the bypass position when the injection is completed.
The Agilent InfinityLab Integrated Column Compartment, an optional upgrade for the Vialsampler, eliminates the need for having a standalone column thermostat in the LC stack. It has the heating capability of reaching temperatures up to 80 °C and can hold a total of two columns with maximum lengths of 30 cm.
For applications requiring control over the vial temperature, the Vialsampler can be equipped with the Agilent InfinityLab Sample Thermostat. It features a vapor-compression refrigeration system and an electric heater, allowing the Vialsampler to reach vial temperatures down to 4 °C and up to 40 °C.
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