The Evaporative Light Scattering Detector is a unique and highly sensitive detector for semi-volatile and non-volatile solutes in a liquid stream. It is mainly used as a concentration detector for High Performance Liquid Chromatography (HPLC). The solvent stream containing the solute material is nebulized and carrieId by a gas flow through an evaporation chamber. The solvent is volatilized, leaving a mist of solute particles that scatter light to a photosensitive device. The signal is amplified and a voltage output provides the concentration of the solute particles passing through the light.
The ELSD may be used alone, or as one of several detectors in a GPC or HPLC system. As the solvent or eluent is evaporated during the analysis, the ELSD must be the last in series if used with other detectors. If the Agilent 1260 Infinity III ELSD or Agilent 1290 Infinity III ELSD is being used as the last detector in a series, care must be taken not to exceed the recommended backpressure in detector cells in other units.
This manual instructs the user in the installation and operation of the Agilent 1260 Infinity III ELSD or Agilent 1290 Infinity III ELSD for standalone use and control using Agilent OpenLab CDS, OpenLab ChemStation, or OpenLab EZChrom.
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id: 4344541707