Large Baseline Offset

1

Inefficient evaporation

Increase the evaporator temperature and/or gas flow.

2

High concentration of non-volatile buffer or stabiliser

High concentration of nonvolatile buffer or stabilizer

Use a lower concentration of stabilizer, unstabilized solvent or, a more volatile buffer (ammonium acetate or ammonium formate).

3

Contaminated diffuser

Perform cleaning procedure.

4

Optics Heater failed

Please contact your Agilent service representative.