Baseline Spikes

Error ID:

Subpages

Probable cause	Suggested actions
1	ProbableCause Particulate matter in the gas supply	Filter the incoming gas, or change the supply.
2	ProbableCause Column shedding	Replace column or fit an inline filter with a 0.2 µm membrane filter directly after the column.
3	ProbableCause Poor nebulization	Check solvent flow rate into ELSD is constant. Check inlet gas flow is >60 psi and stable.
4	Insufficient evaporation	Increase the temperature of the evaporator by 10 °C until the baseline noise decreases.
5	Non-volatile additive in mobile phase Nonvolatile additive in mobile phase	Use a volatile mobile phase.

Probable cause

Suggested actions

ProbableCause

Particulate matter in the gas supply

Filter the incoming gas, or change the supply.

ProbableCause

Column shedding

Replace column or fit an inline filter with a 0.2 µm membrane filter directly after the column.

ProbableCause

Poor nebulization

Check solvent flow rate into ELSD is constant.

Check inlet gas flow is >60 psi and stable.

Insufficient evaporation

Increase the temperature of the evaporator by 10 °C until the baseline noise decreases.

Non-volatile additive in mobile phase

Nonvolatile additive in mobile phase

Use a volatile mobile phase.