Drifting Baseline (RID)

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Probable cause		Suggested actions
1	Room temperature fluctuation NOTE: Give the detector plenty of time for equilibration because it is sensitive to solvent composition, temperature, and flow.	Ensure the system is positioned in a laboratory location free of temperature fluctuations.
2	Inconsistent Mobile Phase Properties NOTE: Flush out contamination, purge the reference cell, and only use stabilized and premixed solvents.	Verify the solvent properties are constant over time.
3	Detector cell contamination	To dissolve any salt crystals formed from buffers, use water to purge the reference cell and flow cell.